LARGE1
LARGE xylosyl- and glucuronyltransferase 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
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biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Defective LARGE causes MDDGA6 and MDDGB6 | ||||
Reactome | Disease | ||||
Reactome | Diseases associated with O-glycosylation of proteins | ||||
Reactome | Diseases of glycosylation | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Defective LARGE causes MDDGA6 and MDDGB6 | ||||
Disease | ||||
Diseases associated with O-glycosylation of proteins | ||||
Diseases of glycosylation | ||||
Metabolism of proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 2 | 3 | 3 | 81.1 | |||||
mathematical ability | 2 | 2 | 2 | 55.2 | |||||
household income | 1 | 2 | 2 | 29.9 | |||||
intelligence | 2 | 2 | 1 | 5.5 | 26.6 | ||||
neuroticism measurement | 1 | 1 | 1 | 17.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 3 | 81.1 | |||||
mathematical ability | 2 | 55.2 | |||||
household income | 2 | 29.9 | |||||
intelligence | 1 | 5.5 | 26.6 | ||||
neuroticism measurement | 1 | 17.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | LARGE xylosyl- and glucuronyltransferase 1 | VGNC:13835 | 470192 | |||||
Mouse | MGI:1342270 | 16795 | ||||||
Dog | LARGE xylosyl- and glucuronyltransferase 1 | VGNC:42585 | 474521 | |||||
Horse | LARGE xylosyl- and glucuronyltransferase 1 | VGNC:19584 | 100068935 | |||||
Chicken | LARGE xylosyl- and glucuronyltransferase 1 | CGNC:50664 | 418062 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | LARGE xylosyl- and glucuronyltransferase 1 | |||||
Mouse | ||||||
Dog | LARGE xylosyl- and glucuronyltransferase 1 | |||||
Horse | LARGE xylosyl- and glucuronyltransferase 1 | |||||
Chicken | LARGE xylosyl- and glucuronyltransferase 1 | |||||
PMID | Year | Title |
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