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Tchem
LAP3
Cytosol aminopeptidase

Protein Summary
Description
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000226299
  • ENSP00000226299
  • ENSG00000002549
  • ENST00000606142
  • ENSP00000476028
  • ENST00000618908
  • ENSP00000481000

Symbol
  • LAPEP
  • PEPS
  • LAP
  • PEPS
  • LAPEP
  • HEL-S-106
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
disease perturbation
0.87
transcription factor binding site profile
0.79
PubMedID
0.77
kinase perturbation
0.76


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 513.04   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 218   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 513.04   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 218   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 30
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1