Tchem LANCL2 LanC-like protein 2

Protein Summary

Description

Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.

Uniprot Accession IDs

• Q9NS86
• B2R8D4
• Q6NSL4
• Q8TCQ3
• Q9BSR1

Gene Name

• LANCL2

Ensembl ID

• ENST00000254770
• ENSP00000254770
• ENSG00000132434

Symbol

• GPR69B
• TASP
• TASP
• GPR69B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.96
transcription factor perturbation	0.94
virus perturbation	0.79
transcription factor binding site profile	0.75
transcription factor	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.07   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 189   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.07   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 189   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0