LAIR2
Leukocyte-associated immunoglobulin-like receptor 2
Protein Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
- ENST00000301202
- ENSP00000301202
- ENSG00000167618
- ENST00000351841
- ENSP00000301203
- ENST00000612901
- ENSP00000478193
- ENSG00000274084
- ENST00000620256
- ENSP00000477747
- ENST00000621280
- ENSP00000480904
- ENSG00000277335
- ENST00000622556
- ENSP00000477535
- CD306
- CD306
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell line | 0.52 | ||
cell type or tissue | 0.52 | ||
tissue | 0.46 | ||
small molecule perturbation | 0.43 | ||
chemical | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.65 (req: < 5)
Gene RIFs: 14 (req: <= 3)
Antibodies: 196 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.65 (req: >= 5)
Gene RIFs: 14 (req: > 3)
Antibodies: 196 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0