L3MBTL1
Lethal(3)malignant brain tumor-like protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.81 | ||
protein domain | 0.73 | ||
molecular function | 0.7 | ||
biological process | 0.68 | ||
tissue sample | 0.67 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Reactome | Regulation of TP53 Activity | ||||
Reactome | Regulation of TP53 Activity through Methylation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
RNA Polymerase II Transcription | ||||
Regulation of TP53 Activity | ||||
Regulation of TP53 Activity through Methylation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 1 | 53.3 | ||||||
mean reticulocyte volume | 1 | 1 | 1 | 46.1 | |||||
monocyte count | 1 | 1 | 1 | 13.6 | |||||
mean platelet volume | 1 | 1 | 1 | 13.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
1 | 53.3 | ||||||
mean reticulocyte volume | 1 | 46.1 | |||||
monocyte count | 1 | 13.6 | |||||
mean platelet volume | 1 | 13.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | L3MBTL1, histone methyl-lysine binding protein | VGNC:14861 | 469947 | |||||
Macaque | L3MBTL1, histone methyl-lysine binding protein | 695694 | ||||||
Mouse | MGI:2676663 | 241764 | ||||||
Rat | RGD:1307316 | 311613 | ||||||
Dog | L3MBTL1, histone methyl-lysine binding protein | VGNC:54652 | 477231 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | L3MBTL1, histone methyl-lysine binding protein | |||||
Macaque | L3MBTL1, histone methyl-lysine binding protein | |||||
Mouse | ||||||
Rat | ||||||
Dog | L3MBTL1, histone methyl-lysine binding protein | |||||
PMID | Year | Title |
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