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Tdark
KRTAP20-2
Keratin-associated protein 20-2

Protein Summary
Description
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330798
  • ENSP00000330746
  • ENSG00000184032

Symbol
  • KAP20.2
  • KAP20.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.58
cell line
0.36
tissue
0.25
cellular component
0.23
protein domain
0.15


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (79)
KRTAP19-5
Tdark
Novelty:  8.16087009
Score:  0.665
Data Source:  STRINGDB
KRTAP19-4
Tdark
Novelty:  217
Score:  0.625
Data Source:  STRINGDB
KRTAP19-7
Tdark
Novelty:  63.61563518
Score:  0.605
Data Source:  STRINGDB
KRTAP19-3
Tdark
Novelty:  1.7849221
Score:  0.602
Data Source:  STRINGDB
KRTAP13-1
Tdark
Novelty:  0.47013888
Score:  0.599
Data Source:  STRINGDB
KRTAP21-2
Tdark
Novelty:  0.86372091
Score:  0.595
Data Source:  STRINGDB
KRTAP22-1
Tdark
Novelty:  0.75498951
Score:  0.585
Data Source:  STRINGDB
KRTAP19-8
Tdark
Novelty:  10.46929825
Score:  0.582
Data Source:  STRINGDB
KRTAP21-1
Tdark
Novelty:  3.10605405
Score:  0.574
Data Source:  STRINGDB
KRTAP6-2
Tdark
Novelty:  1.37501842
Score:  0.573
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Developmental Biology (R-HSA-1266738)

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Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
Keratinization
Name
Explore in Pharos
Explore in Source
Developmental Biology
Keratinization
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.94
PubMed score by year
PubTator Score 1.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title