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Tbio
KRT9
Keratin, type I cytoskeletal 9

Protein Summary
Description
May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000246662
  • ENSP00000246662
  • ENSG00000171403

Symbol
  • K9
  • CK-9
  • EPPK
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
cellular component
0.7
hub protein
0.67
cell line
0.56
cell type or tissue
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 128.72   (req: < 5)
Gene RIFs: 27   (req: <= 3)
Antibodies: 186   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 128.72   (req: >= 5)
Gene RIFs: 27   (req: > 3)
Antibodies: 186   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
KRT1
Tbio
Novelty:  0.00278467
Score:  0.965
Data Source:  STRINGDB
KRT6B
Tbio
Novelty:  0.00152754
Score:  0.936
Data Source:  STRINGDB
KRT6A
Tbio
Novelty:  0.00789111
Score:  0.936
Data Source:  STRINGDB
KRT7
Tbio
Novelty:  0.00039796
Score:  0.936
Data Source:  STRINGDB
KRT4
Tbio
Novelty:  0.00434637
Score:  0.933
Data Source:  STRINGDB
KRT8
Tbio
Novelty:  0.00093008
Score:  0.933
Data Source:  STRINGDB
KRT72
Tbio
Novelty:  0.06391566
Score:  0.932
Data Source:  STRINGDB
KRT5
Tbio
Novelty:  0.00072336
Score:  0.931
Data Source:  STRINGDB
KRT6C
Tbio
Novelty:  0.11659743
Score:  0.93
Data Source:  STRINGDB
KRT3
Tbio
Novelty:  0.00489796
Score:  0.929
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
Keratinization
Name
Explore in Pharos
Explore in Source
Developmental Biology
Keratinization
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
keratin 9
VGNC:9362
454664
Mouse
MGI:96696
107656
Rat
RGD:628785
266717
Dog
keratin 9
VGNC:42537
490980
Cow
keratin 9
VGNC:30745
788727
Species
Name
OMA
EggNOG
Inparanoid
Chimp
keratin 9
Mouse
Rat
Dog
keratin 9
Cow
keratin 9
Publication Statistics
PubMed Score 128.72
PubMed score by year
PubTator Score 127.82
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title