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Tdark
KRBOX1
KRAB domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000383748
  • ENSP00000373254
  • ENSG00000240747
  • ENST00000418176
  • ENSP00000388094
  • ENST00000426937
  • ENSP00000413859
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
1
tissue
0.52
tissue sample
0.49
cell line
0.42
histone modification site profile
0.37


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (9)
RFLNB
Tbio
Novelty:  0.09562879
Score:  0.624
Data Source:  STRINGDB
PPP1R18
Tbio
Novelty:  0.18837599
Score:  0.587
Data Source:  STRINGDB
METTL7B
Tbio
Family:  Enzyme
Novelty:  0.0873748
Score:  0.571
Data Source:  STRINGDB
B3GALT4
Tbio
Family:  Enzyme
Novelty:  0.02308443
Score:  0.543
Data Source:  STRINGDB
ABI3BP
Tbio
Novelty:  0.0916076
Score:  0.533
Data Source:  STRINGDB
LRRC15
Tbio
Novelty:  0.03701624
Score:  0.481
Data Source:  STRINGDB
SLC39A7
Tbio
Family:  Transporter
Novelty:  0.01746862
Score:  0.473
Data Source:  STRINGDB
MPP5
Tbio
Novelty:  0.01707773
Score:  0.444
Data Source:  STRINGDB
HSPA1B
Tbio
Novelty:  0.01429214
Score:  0.427
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
4
4
5
98.9
monocyte percentage of leukocytes
2
3
4
97.9
myeloid white cell count
2
3
3
94.4
granulocyte percentage of myeloid white cells
1
2
2
93.9
eotaxin measurement
1
3
3
93.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
5
98.9
monocyte percentage of leukocytes
4
97.9
myeloid white cell count
3
94.4
granulocyte percentage of myeloid white cells
2
93.9
eotaxin measurement
3
93.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
KRAB box domain containing 1
100614118
Macaque
family with sequence similarity 198 member A [Source:HGNC Symbol;Acc:HGNC:24485]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
KRAB box domain containing 1
Macaque
family with sequence similarity 198 member A [Source:HGNC Symbol;Acc:HGNC:24485]
Publication Statistics
PubMed Score 0.27
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title