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Tdark
KRBA1
Protein KRBA1

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 17   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 17   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
SHCBP1
Tbio
Novelty:  0.09160318
p_int:  0.999999248
p_ni:  7.52e-7
Data Source:  BioPlex
P3H2
Tbio
Family:  Enzyme
Novelty:  0.04237396
p_int:  0.999997627
p_ni:  0.000002353
p_wrong:  2e-8
Score:  0.173
Data Source:  BioPlex,STRINGDB
TBCCD1
Tbio
Novelty:  0.21991508
p_int:  0.999988553
p_ni:  0.000011228
p_wrong:  2.2e-7
Score:  0.588
Data Source:  BioPlex,STRINGDB
CDC16
Tbio
Novelty:  0.00916715
p_int:  0.99991439
p_ni:  0.00008561
Data Source:  BioPlex
PPP2R3B
Tbio
Family:  Enzyme
Novelty:  0.02932064
p_int:  0.999858986
p_ni:  0.000140999
p_wrong:  1.6e-8
Score:  0.54
Data Source:  BioPlex,STRINGDB
P3H1
Tbio
Family:  Enzyme
Novelty:  0.02067711
p_int:  0.999419425
p_ni:  0.000580575
Data Source:  BioPlex
PRMT2
Tbio
Family:  Epigenetic
Novelty:  0.04121581
p_int:  0.998952665
p_ni:  0.001047308
p_wrong:  2.8e-8
Data Source:  BioPlex
SSSCA1
Tdark
Novelty:  0.53523038
p_int:  0.998687934
p_ni:  0.001312066
Data Source:  BioPlex
P4HA2
Tbio
Family:  Enzyme
Novelty:  0.02097718
p_int:  0.995263614
p_ni:  0.004627672
p_wrong:  0.000108714
Data Source:  BioPlex
THSD4
Tbio
Novelty:  0.12898073
p_int:  0.991440118
p_ni:  0.008540107
p_wrong:  0.000019775
Score:  0.155
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosaic loss of chromosome Y measurement
2
1
2
89
pulse pressure measurement
1
1
1
61.7
platelet crit
1
1
1
53.1
systolic blood pressure change measurement
1
1
0
73.7
40.6
reticulocyte measurement
1
1
1
21.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosaic loss of chromosome Y measurement
2
89
pulse pressure measurement
1
61.7
platelet crit
1
53.1
systolic blood pressure change measurement
0
73.7
40.6
reticulocyte measurement
1
21.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
KRAB-A domain containing 1
711863
Mouse
MGI:1925077
77827
Rat
RGD:1306967
362358
Dog
KRAB-A domain containing 1
VGNC:42509
610822
Horse
KRAB-A domain containing 1
VGNC:19513
100062579
Species
Name
OMA
EggNOG
Inparanoid
Macaque
KRAB-A domain containing 1
Mouse
Rat
Dog
KRAB-A domain containing 1
Horse
KRAB-A domain containing 1
Publication Statistics
PubMed Score 1.45
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title