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Tdark
KLRG2
Killer cell lectin-like receptor subfamily G member 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340940
  • ENSP00000339356
  • ENSG00000188883
  • ENST00000393039
  • ENSP00000376759

Symbol
  • CLEC15B
  • CLEC15B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.65
cell type or tissue
0.56
PubMedID
0.5
transcription factor
0.46
cell line
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.91   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.91   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (77)
FGFRL1
Tbio
Novelty:  0.02178846
p_int:  0.999997129
p_ni:  0.000002831
p_wrong:  4e-8
Score:  0.201
Data Source:  BioPlex,STRINGDB
EPHB1
Tchem
Family:  Kinase
Novelty:  0.01424716
p_int:  0.999996812
p_ni:  1.44e-7
p_wrong:  0.000003044
Score:  0.243
Data Source:  BioPlex,STRINGDB
ZDHHC6
Tbio
Family:  Enzyme
Novelty:  0.17384821
p_int:  0.999995232
p_ni:  0.000004755
p_wrong:  1.3e-8
Data Source:  BioPlex
LTBP1
Tbio
Novelty:  0.00958396
p_int:  0.999992098
p_ni:  0.000007902
Data Source:  BioPlex
WNT11
Tbio
Novelty:  0.0045754
p_int:  0.999981231
p_ni:  0.000002386
p_wrong:  0.000016384
Score:  0.173
Data Source:  BioPlex,STRINGDB
GLRX3
Tbio
Novelty:  0.0096265
p_int:  0.999965695
p_ni:  0.000034305
Score:  0.455
Data Source:  BioPlex,STRINGDB
F5
Tbio
Novelty:  0.00161772
p_int:  0.999939008
p_ni:  0.000026842
p_wrong:  0.00003415
Score:  0.185
Data Source:  BioPlex,STRINGDB
APBA2
Tbio
Novelty:  0.01654185
p_int:  0.999915563
p_ni:  0.000084318
p_wrong:  1.19e-7
Score:  0.197
Data Source:  BioPlex,STRINGDB
HTR2C
Tclin
Family:  GPCR
Novelty:  0.00074287
p_int:  0.999853041
p_ni:  0.000146951
p_wrong:  8e-9
Data Source:  BioPlex
STBD1
Tbio
Novelty:  0.08362185
p_int:  0.999792467
p_ni:  0.000083977
p_wrong:  0.000123555
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
left ventricular diastolic function measurement
1
1
0
1.7
21.5
high density lipoprotein cholesterol measurement
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
left ventricular diastolic function measurement
0
1.7
21.5
high density lipoprotein cholesterol measurement
1
17.8
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
killer cell lectin like receptor G2
VGNC:7397
472531
Macaque
killer cell lectin like receptor G2 [Source:HGNC Symbol;Acc:HGNC:24778]
Mouse
MGI:1921503
74253
Rat
RGD:1587495
689885
Cow
killer cell lectin like receptor G2
VGNC:30688
531720
Species
Name
OMA
EggNOG
Inparanoid
Chimp
killer cell lectin like receptor G2
Macaque
killer cell lectin like receptor G2 [Source:HGNC Symbol;Acc:HGNC:24778]
Mouse
Rat
Cow
killer cell lectin like receptor G2
Publication Statistics
PubMed Score 0.91
PubMed score by year
PubTator Score 1.50
PubTator score by year
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Related Publications
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PMID
Year
Title