You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
KLHL36
Kelch-like protein 36

Protein Summary
Description
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258157
  • ENSP00000258157
  • ENSG00000135686
  • ENST00000564996
  • ENSP00000456743

Symbol
  • C16orf44
  • C16orf44
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
small molecule perturbation
0.69
histone modification site profile
0.6
tissue sample
0.58
cell line
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0