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Tdark
KLHL34
Kelch-like protein 34

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000379499
  • ENSP00000368813
  • ENSG00000185915
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
cell type or tissue
0.77
cell line
0.53
chemical
0.41
PubMedID
0.38


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.83   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 29   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.83   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 29   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.990645996
p_ni:  0.009354004
Data Source:  BioPlex
STUB1
Tbio
Family:  Enzyme
Novelty:  0.00055102
p_int:  0.987572256
p_ni:  0.012427744
Score:  0.196
Data Source:  BioPlex,STRINGDB
BAG1
Tbio
Novelty:  0.00285515
p_int:  0.949836843
p_ni:  0.04935478
p_wrong:  0.000808377
Score:  0.179
Data Source:  BioPlex,STRINGDB
HSPA2
Tchem
Novelty:  0.01696667
p_int:  0.937995065
p_ni:  0.062004935
Score:  0.531
Data Source:  BioPlex,STRINGDB
BAG3
Tbio
Novelty:  0.0042967
p_int:  0.922000882
p_ni:  0.077999118
Score:  0.168
Data Source:  BioPlex,STRINGDB
HSPA1B
Tbio
Novelty:  0.01429214
p_int:  0.88162142
p_ni:  0.11837858
Score:  0.275
Data Source:  BioPlex,STRINGDB
STIP1
Tbio
Novelty:  0.00590952
p_int:  0.856947299
p_ni:  0.143052701
Score:  0.165
Data Source:  BioPlex,STRINGDB
HSPA6
Tbio
Novelty:  0.00654285
p_int:  0.796959829
p_ni:  0.203040171
Score:  0.155
Data Source:  BioPlex,STRINGDB
CCT2
Tbio
Novelty:  0.01967139
p_int:  0.767377052
p_ni:  0.232622948
Data Source:  BioPlex
SMPX
Tbio
Novelty:  0.05084864
Score:  0.788
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
kelch like family member 34
VGNC:14693
473860
Macaque
kelch like family member 34
696156
Mouse
MGI:2685234
245683
Rat
RGD:1560439
302703
Dog
kelch like family member 34
VGNC:42467
491769
Species
Name
OMA
EggNOG
Inparanoid
Chimp
kelch like family member 34
Macaque
kelch like family member 34
Mouse
Rat
Dog
kelch like family member 34
Publication Statistics
PubMed Score 0.83
PubMed score by year
PubTator Score 0.53
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title