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Tbio
KLHL29
Kelch-like protein 29

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.86   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.86   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
KBTBD8
Tbio
Novelty:  0.42601278
p_int:  0.99999876
p_ni:  0.000001222
p_wrong:  1.8e-8
Score:  0.825
Data Source:  BioPlex,STRINGDB
ZBTB10
Tbio
Family:  TF
Novelty:  0.05707286
p_int:  0.999958446
p_ni:  0.000041553
p_wrong:  1e-9
Score:  0.557
Data Source:  BioPlex,STRINGDB
NPHP3
Tbio
Novelty:  0.02857926
p_int:  0.999642835
p_ni:  0.000357165
Score:  0.211
Data Source:  BioPlex,STRINGDB
ZNF232
Tdark
Family:  TF
Novelty:  0.68288358
p_int:  0.989611925
p_ni:  0.000251726
p_wrong:  0.01013635
Score:  0.226
Data Source:  BioPlex,STRINGDB
KLHL21
Tbio
Novelty:  0.20694121
p_int:  0.988225095
p_ni:  0.001231439
p_wrong:  0.010543466
Score:  0.297
Data Source:  BioPlex,STRINGDB
NUDCD3
Tbio
Novelty:  0.32026811
p_int:  0.927990589
p_ni:  0.072009411
Score:  0.183
Data Source:  BioPlex,STRINGDB
KBTBD7
Tdark
Novelty:  0.4947466
p_int:  0.918096242
p_ni:  0.081809228
p_wrong:  0.000094529
Data Source:  BioPlex
MOXD1
Tbio
Family:  Enzyme
Novelty:  0.00571213
Score:  0.69
Data Source:  STRINGDB
SNX9
Tbio
Novelty:  0.01737783
Score:  0.677
Data Source:  STRINGDB
ADCY3
Tbio
Family:  Enzyme
Novelty:  0.00260265
Score:  0.673
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (36)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
3
5
6
95.1
appendicular lean mass
3
1
3
86.1
reticulocyte count
1
1
1
86
reticulocyte measurement
1
1
1
85.7
birth weight
4
4
4
83.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
6
95.1
appendicular lean mass
3
86.1
reticulocyte count
1
86
reticulocyte measurement
1
85.7
birth weight
4
83.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
kelch like family member 29
VGNC:282
470324
Macaque
kelch like family member 29
718309
Mouse
MGI:2683857
208439
Rat
RGD:1311076
298867
Dog
kelch like family member 29
VGNC:42462
482991
Species
Name
OMA
EggNOG
Inparanoid
Chimp
kelch like family member 29
Macaque
kelch like family member 29
Mouse
Rat
Dog
kelch like family member 29
Publication Statistics
PubMed Score 1.86
PubMed score by year
PubTator Score 0.64
PubTator score by year
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Related Publications
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PMID
Year
Title