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Tdark
KLHL26
Kelch-like protein 26

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300976
  • ENSP00000300976
  • ENSG00000167487
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
histone modification site profile
0.9
tissue sample
0.7
kinase perturbation
0.66
transcription factor
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.98   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 105   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.98   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
NUDCD3
Tbio
Novelty:  0.32026811
p_int:  0.99994138
p_ni:  0.00005862
Data Source:  BioPlex
IPP
Tbio
Novelty:  0.12841634
p_int:  0.999909108
p_ni:  0.000090706
p_wrong:  1.85e-7
Data Source:  BioPlex
KLHL28
Tdark
Novelty:  1.1777024
p_int:  0.999875675
p_ni:  0.000124325
Score:  0.768
Data Source:  BioPlex,STRINGDB
KLHL14
Tbio
Novelty:  0.1214402
p_int:  0.999765149
p_ni:  0.000234851
Score:  0.55
Data Source:  BioPlex,STRINGDB
KLHL22
Tbio
Novelty:  0.24456252
p_int:  0.997796528
p_ni:  0.002203472
Score:  0.334
Data Source:  BioPlex,STRINGDB
KLHL9
Tdark
Novelty:  0.22434722
p_int:  0.995821149
p_ni:  0.004178851
Data Source:  BioPlex
FAM241A
Tdark
Novelty:  1.04041354
p_int:  0.993459695
p_ni:  0.006540305
Data Source:  BioPlex
KLHL20
Tbio
Novelty:  0.12205871
p_int:  0.992547365
p_ni:  0.007452635
Score:  0.201
Data Source:  BioPlex,STRINGDB
CCT6B
Tdark
Novelty:  0.28933315
p_int:  0.989867057
p_ni:  0.010132943
Data Source:  BioPlex
CUL3
Tbio
Novelty:  0.0028737
p_int:  0.989494114
p_ni:  0.010505886
Score:  0.491
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
5
3
6
90.4
Oral ulcer
1
1
0
1.1
73
body height
1
1
1
71.2
growth differentiation factor 15 measurement
1
1
1
67.8
visceral adipose tissue measurement
1
1
1
59.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
6
90.4
Oral ulcer
0
1.1
73
body height
1
71.2
growth differentiation factor 15 measurement
1
67.8
visceral adipose tissue measurement
1
59.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
kelch like family member 26
VGNC:3628
468772
Mouse
MGI:2443079
234378
Rat
RGD:1312034
290657
Dog
kelch like family member 26
VGNC:42460
484817
Horse
kelch like family member 26 [Source:HGNC Symbol;Acc:HGNC:25623]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
kelch like family member 26
Mouse
Rat
Dog
kelch like family member 26
Horse
kelch like family member 26 [Source:HGNC Symbol;Acc:HGNC:25623]
Publication Statistics
PubMed Score 0.98
PubMed score by year
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Related Publications
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PMID
Year
Title