KLF4
Krueppel-like factor 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
gene perturbation | 1 | ||
PubMedID | 1 | ||
molecular function | 0.99 | ||
virus perturbation | 0.98 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | FOXO-mediated transcription | ||||
Reactome | FOXO-mediated transcription of cell cycle genes | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
FOXO-mediated transcription | ||||
FOXO-mediated transcription of cell cycle genes | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Mutant Phenotype (IMP) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 0 | 1.4 | 12.3 | |||||
2 | 1 | 0 | 1.1 | 7.9 | |||||
glomerular filtration rate | 1 | 1 | 1 | 3.6 | |||||
creatinine measurement | 1 | 1 | 1 | 3.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.4 | 12.3 | |||||
0 | 1.1 | 7.9 | |||||
glomerular filtration rate | 1 | 3.6 | |||||
creatinine measurement | 1 | 3.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | Kruppel like factor 4 | VGNC:13903 | 464640 | |||||
Macaque | Kruppel like factor 4 | 711169 | ||||||
Mouse | MGI:1342287 | 16600 | ||||||
Rat | RGD:621445 | 114505 | ||||||
Dog | Kruppel like factor 4 | 481657 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | Kruppel like factor 4 | |||||
Macaque | Kruppel like factor 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | Kruppel like factor 4 | |||||
PMID | Year | Title |
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