Tbio KIFC2 Kinesin-like protein KIFC2

Protein Summary

Description

May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites (By similarity).

Uniprot Accession IDs

• Q96AC6
• E9PHB2
• Q96NN6

Gene Name

• KIFC2

Ensembl ID

• ENST00000301332
• ENSP00000301332
• ENSG00000167702

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.98
cell type or tissue	0.8
virus perturbation	0.68
protein domain	0.58
cell line	0.55

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Microtubule Binding Motor Protein / Kinesin-like Protein Kifc2

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Microtubule Binding Motor Protein / Kinesin-like Protein Kifc2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.3   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 72   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.3   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0