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Tchem
KIFC1
Kinesin-like protein KIFC1

Protein Summary
Description
Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374523
  • ENSP00000363647
  • ENSG00000204197
  • ENST00000428849
  • ENSP00000393963
  • ENSG00000237649
  • ENST00000448818
  • ENSP00000407885
  • ENSG00000233450

Symbol
  • HSET
  • KNSL2
  • HSET
  • KNSL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein complex
1
molecular function
0.98
interacting protein
0.92
gene perturbation
0.77
PubMedID
0.76


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 142.06   (req: < 5)
Gene RIFs: 28   (req: <= 3)
Antibodies: 130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 142.06   (req: >= 5)
Gene RIFs: 28   (req: > 3)
Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 11
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0