You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
KIF1BP
KIF1-binding protein

Protein Summary
Description
Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratrico peptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating transport of the mitochondria. Mutations in this gene are associated with Goldberg-Shprintzen megacolon syndrome. [provided by RefSeq, Mar 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361983
  • ENSP00000354848
  • ENSG00000198954

Symbol
  • KBP
  • KIAA1279
  • KBP
  • TTC20
  • KIAA1279
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
interacting protein
0.83
kinase perturbation
0.81
transcription factor binding site profile
0.71
tissue
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.65   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.65   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0