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Tbio
KIF17
Kinesin-like protein KIF17

Protein Summary
Description
Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000247986
  • ENSP00000247986
  • ENSG00000117245
  • ENST00000400463
  • ENSP00000383311

Symbol
  • KIAA1405
  • KIF3X
  • KIF3X
  • KLP-2
  • OSM-3
  • KIF17B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.98
virus perturbation
0.79
cellular component
0.7
histone modification site profile
0.68
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 142.86   (req: < 5)
Gene RIFs: 15   (req: <= 3)
Antibodies: 108   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 142.86   (req: >= 5)
Gene RIFs: 15   (req: > 3)
Antibodies: 108   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (153)
KIFAP3
Tbio
Novelty:  0.01902437
Score:  0.971
Data Source:  STRINGDB
FHL5
Tbio
Novelty:  0.27618006
Score:  0.968
Data Source:  STRINGDB
XPO1
Tclin
Novelty:  0.00078187
Score:  0.968
Data Source:  STRINGDB
IFT52
Tbio
Novelty:  0.04183122
Score:  0.967
Data Source:  STRINGDB
DYNC2H1
Tbio
Novelty:  0.01306616
Score:  0.965
Data Source:  STRINGDB
IFT88
Tbio
Novelty:  0.00727114
Score:  0.964
Data Source:  STRINGDB
TNPO1
Tbio
Novelty:  0.01278619
Score:  0.964
Data Source:  Reactome,STRINGDB
TTC26
Tbio
Novelty:  0.10088384
Score:  0.963
Data Source:  STRINGDB
CREM
Tbio
Family:  TF
Novelty:  0.00331358
Score:  0.963
Data Source:  STRINGDB
IFT57
Tbio
Novelty:  0.03373199
Score:  0.963
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (8)
Activation of NMDA receptors and postsynaptic events (R-HSA-442755)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Activation of NMDA receptors and postsynaptic events
Reactome
Assembly and cell surface presentation of NMDA receptors
Reactome
Cilium Assembly
Reactome
Intraflagellar transport
Reactome
Neuronal System
Name
Explore in Pharos
Explore in Source
Activation of NMDA receptors and postsynaptic events
Assembly and cell surface presentation of NMDA receptors
Cilium Assembly
Intraflagellar transport
Neuronal System
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (20)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
3
3
2
8.4
93.9
chronotype measurement
2
2
1
1
88.4
mean reticulocyte volume
1
1
1
75
mean corpuscular volume
1
1
1
73.9
apolipoprotein A 1 measurement
1
1
1
61.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
2
8.4
93.9
chronotype measurement
1
1
88.4
mean reticulocyte volume
1
75
mean corpuscular volume
1
73.9
apolipoprotein A 1 measurement
1
61.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
kinesin family member 17
VGNC:1287
456592
Mouse
MGI:1098229
16559
Rat
RGD:1562511
500571
Dog
kinesin family member 17
VGNC:42386
100688382
Horse
kinesin family member 17
VGNC:19397
100058362
Species
Name
OMA
EggNOG
Inparanoid
Chimp
kinesin family member 17
Mouse
Rat
Dog
kinesin family member 17
Horse
kinesin family member 17
Publication Statistics
PubMed Score 142.86
PubMed score by year
PubTator Score 70.61
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title