You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
KIAA1257
Uncharacterized protein KIAA1257

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265068
  • ENSP00000265068
  • ENSG00000114656
  • ENST00000515659
  • ENSP00000422539
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.63
histone modification site profile
0.6
tissue
0.6
cell line
0.53
cell type or tissue
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (10)
Q6ZUG5
Tdark
Novelty:  17.1875
Score:  0.607
Data Source:  STRINGDB
FBXO46
Tdark
Novelty:  1.45550259
Score:  0.58
Data Source:  STRINGDB
TMEM211
Tdark
Novelty:  6.51386952
Score:  0.57
Data Source:  STRINGDB
LCE1F
Tdark
Novelty:  1.56312927
Score:  0.541
Data Source:  STRINGDB
JOSD1
Tbio
Novelty:  0.20367997
Score:  0.502
Data Source:  STRINGDB
TAF5L
Tbio
Family:  Enzyme
Novelty:  0.29525944
Score:  0.473
Data Source:  STRINGDB
MLF2
Tbio
Novelty:  0.08982141
Score:  0.473
Data Source:  STRINGDB
FRG1
Tbio
Novelty:  0.0292811
Score:  0.418
Data Source:  STRINGDB
ZMYM3
Tbio
Novelty:  0.06911008
Score:  0.412
Data Source:  STRINGDB
ADAMTS6
Tbio
Family:  Enzyme
Novelty:  0.08054942
Score:  0.4
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
2
2
75
mean platelet volume
2
1
2
74.5
platelet crit
1
1
1
49.3
BMI-adjusted hip circumference
2
1
2
37
BMI-adjusted waist-hip ratio
2
1
2
18.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
75
mean platelet volume
2
74.5
platelet crit
1
49.3
BMI-adjusted hip circumference
2
37
BMI-adjusted waist-hip ratio
2
18.4
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Horse
KIAA1257 [Source:HGNC Symbol;Acc:HGNC:29231]
Cow
KIAA1257 [Source:HGNC Symbol;Acc:HGNC:29231]
Species
Name
OMA
EggNOG
Inparanoid
Horse
KIAA1257 [Source:HGNC Symbol;Acc:HGNC:29231]
Cow
KIAA1257 [Source:HGNC Symbol;Acc:HGNC:29231]
Publication Statistics
PubMed Score 0.12
PubMed score by year
PubTator Score 0.13
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title