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Tdark
KIAA1143
Uncharacterized protein KIAA1143

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296121
  • ENSP00000296121
  • ENSG00000163807
  • ENST00000627745
  • ENSP00000486878
  • ENSG00000281665
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
transcription factor binding site profile
0.67
transcription factor perturbation
0.61
cell type or tissue
0.55
tissue sample
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
AQR
Tbio
Novelty:  0.00434312
p_int:  0.999689423
p_ni:  0.000310577
Score:  0.205
Data Source:  BioPlex,STRINGDB
CRNKL1
Tbio
Novelty:  0.10274174
p_int:  0.999319662
p_ni:  0.000680338
Score:  0.159
Data Source:  BioPlex,STRINGDB
XAB2
Tbio
Novelty:  0.04104647
p_int:  0.999260189
p_ni:  0.000739811
Score:  0.205
Data Source:  BioPlex,STRINGDB
C1orf162
Tdark
Novelty:  4.98517033
p_int:  0.994077708
p_ni:  0.005922292
Score:  0.188
Data Source:  BioPlex,STRINGDB
WDR83
Tbio
Novelty:  0.11602568
p_int:  0.994019658
p_ni:  0.005897184
p_wrong:  0.000083158
Score:  0.665
Data Source:  BioPlex,STRINGDB
ISY1
Tdark
Novelty:  1.68602768
p_int:  0.991765832
p_ni:  0.008091343
p_wrong:  0.000142826
Data Source:  BioPlex
DHX35
Tdark
Family:  Enzyme
Novelty:  0.26052594
p_int:  0.991055325
p_ni:  0.008944607
p_wrong:  6.8e-8
Score:  0.306
Data Source:  BioPlex,STRINGDB
BUD31
Tbio
Novelty:  0.13364384
p_int:  0.989546909
p_ni:  0.010451806
p_wrong:  0.000001285
Score:  0.542
Data Source:  BioPlex,STRINGDB
ECD
Tbio
Novelty:  0.06070487
p_int:  0.989476321
p_ni:  0.010523678
Score:  0.696
Data Source:  BioPlex,STRINGDB
CDC40
Tbio
Novelty:  0.03139044
p_int:  0.988770263
p_ni:  0.011229663
p_wrong:  7.4e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (16)
Items per page:
1 – 5 of 16
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.5
60.5
1
1
0
1.5
60.5
pulse pressure measurement
1
1
1
50.6
pulse pressure measurement
1
1
1
50.6
macrophage inflammatory protein 1b measurement
1
1
1
35
Items per page:
1 – 5 of 16
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.5
60.5
0
1.5
60.5
pulse pressure measurement
1
50.6
pulse pressure measurement
1
50.6
macrophage inflammatory protein 1b measurement
1
35
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
KIAA1143
VGNC:11421
739627
Macaque
KIAA1143 ortholog
714979
Mouse
MGI:1913452
66202
Rat
RGD:1311745
301079
Dog
KIAA1143
VGNC:42358
476657
Species
Name
OMA
EggNOG
Inparanoid
Chimp
KIAA1143
Macaque
KIAA1143 ortholog
Mouse
Rat
Dog
KIAA1143
Publication Statistics
PubMed Score 0.16
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title