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Tdark
KIAA0232
Uncharacterized protein KIAA0232

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307659
  • ENSP00000303928
  • ENSG00000170871
  • ENST00000425103
  • ENSP00000413739
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.86
transcription factor perturbation
0.84
disease perturbation
0.83
microRNA
0.73
molecular function
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.4   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 20   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.4   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
FANCD2OS
Tdark
Novelty:  9.51798561
p_int:  0.99976492
p_ni:  0.000233755
p_wrong:  0.000001326
Data Source:  BioPlex
IQCN
Tdark
Novelty:  2.74045479
p_int:  0.998840188
p_ni:  0.001159812
Data Source:  BioPlex
ZBBX
Tdark
Novelty:  1.66474399
p_int:  0.998387697
p_ni:  0.001612303
Data Source:  BioPlex
PIP
Tbio
Novelty:  0.00208509
p_int:  0.997458294
p_ni:  0.002541706
Data Source:  BioPlex
SSH3
Tbio
Family:  Enzyme
Novelty:  0.11388661
p_int:  0.997349852
p_ni:  0.00264848
p_wrong:  0.000001668
Data Source:  BioPlex
FOXD4L6
Tdark
Family:  TF
Novelty:  9.78461538
p_int:  0.996747128
p_ni:  0.003252825
p_wrong:  4.7e-8
Data Source:  BioPlex
USP36
Tbio
Family:  Enzyme
Novelty:  0.02779727
p_int:  0.994526265
p_ni:  0.005473735
p_wrong:  1e-9
Score:  0.234
Data Source:  BioPlex,STRINGDB
ADAMTS4
Tchem
Family:  Enzyme
Novelty:  0.00424194
p_int:  0.993115454
p_ni:  0.006884433
p_wrong:  1.13e-7
Data Source:  BioPlex
FRMD1
Tdark
Novelty:  0.96833141
p_int:  0.988603845
p_ni:  0.011314615
p_wrong:  0.00008154
Data Source:  BioPlex
RPL28
Tbio
Novelty:  0.03136035
p_int:  0.988374343
p_ni:  0.011625657
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
4
7
8
99
platelet count
5
4
4
5.7
98.9
neutrophil count
3
2
3
79.6
leukocyte count
2
2
2
67.7
myeloid white cell count
1
1
1
67.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
8
99
platelet count
4
5.7
98.9
neutrophil count
3
79.6
leukocyte count
2
67.7
myeloid white cell count
1
67.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
KIAA0232
VGNC:2076
461106
Macaque
KIAA0232 ortholog
710141
Mouse
MGI:1261849
320661
Rat
RGD:1596848
680039
Dog
KIAA0232
VGNC:42342
610307
Species
Name
OMA
EggNOG
Inparanoid
Chimp
KIAA0232
Macaque
KIAA0232 ortholog
Mouse
Rat
Dog
KIAA0232
Publication Statistics
PubMed Score 0.40
PubMed score by year
PubTator Score 0.43
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title