KDM4A
Lysine-specific demethylase 4A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.85 | ||
cell type or tissue | 0.78 | ||
transcription factor binding site profile | 0.76 | ||
biological process | 0.75 | ||
molecular function | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Chromatin modifying enzymes | ||||
Reactome | Chromatin organization | ||||
Reactome | DNA Double Strand Break Response | ||||
Reactome | DNA Double-Strand Break Repair | ||||
Reactome | DNA Repair | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Chromatin modifying enzymes | ||||
Chromatin organization | ||||
DNA Double Strand Break Response | ||||
DNA Double-Strand Break Repair | ||||
DNA Repair | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 5 | 5 | 6 | 95.1 | |||||
mathematical ability | 4 | 2 | 4 | 90.9 | |||||
smoking initiation | 3 | 3 | 3 | 89.7 | |||||
alkaline phosphatase measurement | 2 | 2 | 1 | 7.3 | 89 | ||||
7 | 4 | 2 | 1.1 | 81.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 6 | 95.1 | |||||
mathematical ability | 4 | 90.9 | |||||
smoking initiation | 3 | 89.7 | |||||
alkaline phosphatase measurement | 1 | 7.3 | 89 | ||||
2 | 1.1 | 81.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | lysine demethylase 4A | VGNC:8061 | 456829 | |||||
Macaque | lysine demethylase 4A | 701272 | ||||||
Mouse | MGI:2446210 | 230674 | ||||||
Rat | RGD:1306378 | 313539 | ||||||
Dog | lysine demethylase 4A | VGNC:42324 | 482530 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | lysine demethylase 4A | |||||
Macaque | lysine demethylase 4A | |||||
Mouse | ||||||
Rat | ||||||
Dog | lysine demethylase 4A | |||||
PMID | Year | Title |
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