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Tdark
KCTD19
BTB/POZ domain-containing protein KCTD19

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304372
  • ENSP00000305702
  • ENSG00000168676
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.81
cell type or tissue
0.74
histone modification site profile
0.74
tissue sample
0.66
virus perturbation
0.55


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.31   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.31   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (217)
BOP1
Tbio
Novelty:  0.03512044
Score:  0.963
Data Source:  STRINGDB
RPF1
Tdark
Novelty:  3.67047505
Score:  0.95
Data Source:  STRINGDB
NIFK
Tbio
Novelty:  0.01221562
Score:  0.936
Data Source:  STRINGDB
PES1
Tbio
Novelty:  0.07162845
Score:  0.932
Data Source:  STRINGDB
WDR12
Tbio
Novelty:  0.03409059
Score:  0.929
Data Source:  STRINGDB
DDX55
Tdark
Family:  Enzyme
Novelty:  0.27887497
Score:  0.928
Data Source:  STRINGDB
NOC3L
Tbio
Novelty:  0.05635731
Score:  0.919
Data Source:  STRINGDB
BRIX1
Tbio
Novelty:  0.16561444
Score:  0.911
Data Source:  STRINGDB
FTSJ3
Tbio
Family:  Enzyme
Novelty:  0.01888973
Score:  0.911
Data Source:  STRINGDB
NOP58
Tbio
Novelty:  0.02148045
Score:  0.9
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
7
5
11
92.7
heel bone mineral density
2
2
5
91.7
mean corpuscular volume
1
4
4
87.9
mean reticulocyte volume
2
4
5
85.9
BMI-adjusted waist circumference
6
6
9
78.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
11
92.7
heel bone mineral density
5
91.7
mean corpuscular volume
4
87.9
mean reticulocyte volume
5
85.9
BMI-adjusted waist circumference
9
78.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
potassium channel tetramerization domain containing 19
VGNC:8984
467999
Macaque
potassium channel tetramerization domain containing 19
699297
Mouse
MGI:3045294
279499
Rat
RGD:1561326
291965
Dog
potassium channel tetramerization domain containing 19
VGNC:42304
479689
Species
Name
OMA
EggNOG
Inparanoid
Chimp
potassium channel tetramerization domain containing 19
Macaque
potassium channel tetramerization domain containing 19
Mouse
Rat
Dog
potassium channel tetramerization domain containing 19
Publication Statistics
PubMed Score 2.31
PubMed score by year
PubTator Score 0.67
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title