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Tdark
KCTD18
BTB/POZ domain-containing protein KCTD18

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359878
  • ENSP00000352941
  • ENSG00000155729
  • ENST00000409157
  • ENSP00000386751

Symbol
  • 6530404F10Rik
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
transcription factor binding site profile
0.65
cellular component
0.6
tissue sample
0.59
cell line
0.54


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.99   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.99   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
LRP1
Tbio
Novelty:  0.00200788
p_int:  0.999921441
p_ni:  1.16e-7
p_wrong:  0.000078443
Score:  0.237
Data Source:  BioPlex,STRINGDB
NTF3
Tbio
Novelty:  0.00089023
p_int:  0.999607417
p_ni:  0.000004662
p_wrong:  0.000387921
Data Source:  BioPlex
KCTD19
Tdark
Novelty:  1.14527788
Score:  0.782
Data Source:  STRINGDB
SPATS2L
Tbio
Novelty:  0.03619189
Score:  0.767
Data Source:  STRINGDB
KCTD20
Tdark
Novelty:  0.47655751
Score:  0.754
Data Source:  STRINGDB
TYW5
Tbio
Novelty:  0.1382439
Score:  0.729
Data Source:  STRINGDB
BZW1
Tbio
Novelty:  0.11677238
Score:  0.679
Data Source:  STRINGDB
KCNK16
Tbio
Family:  IC
Novelty:  0.09168043
Score:  0.598
Data Source:  STRINGDB
KCNG2
Tclin
Family:  IC
Novelty:  0.31296944
Score:  0.592
Data Source:  STRINGDB
KCTD11
Tchem
Novelty:  0.11239142
Score:  0.591
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
potassium channel tetramerization domain containing 18
VGNC:2361
459861
Macaque
potassium channel tetramerization domain containing 18
699824
Mouse
MGI:3603813
51960
Rat
RGD:1564820
301436
Dog
potassium channel tetramerization domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26446]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
potassium channel tetramerization domain containing 18
Macaque
potassium channel tetramerization domain containing 18
Mouse
Rat
Dog
potassium channel tetramerization domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26446]
Publication Statistics
PubMed Score 0.99
PubMed score by year
PubTator Score 0.83
PubTator score by year
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Related Publications
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PMID
Year
Title