KCNN4
Intermediate conductance calcium-activated potassium channel protein 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.91 | ||
molecular function | 0.91 | ||
kinase perturbation | 0.88 | ||
small molecule perturbation | 0.74 | ||
biological process | 0.69 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Ca2+ activated K+ channels | ||||
Reactome | Neuronal System | ||||
Reactome | Potassium Channels | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Ca2+ activated K+ channels | ||||
Neuronal System | ||||
Potassium Channels | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
monocyte percentage of leukocytes | 2 | 2 | 2 | 94.1 | |||||
apolipoprotein B measurement | 1 | 2 | 2 | 92.4 | |||||
low density lipoprotein cholesterol measurement | 1 | 2 | 2 | 90.8 | |||||
hemoglobin measurement | 3 | 2 | 3 | 82.7 | |||||
monocyte count | 1 | 1 | 1 | 81.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
monocyte percentage of leukocytes | 2 | 94.1 | |||||
apolipoprotein B measurement | 2 | 92.4 | |||||
low density lipoprotein cholesterol measurement | 2 | 90.8 | |||||
hemoglobin measurement | 3 | 82.7 | |||||
monocyte count | 1 | 81.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | potassium calcium-activated channel subfamily N member 4 | VGNC:7484 | 456098 | |||||
Mouse | MGI:1277957 | 16534 | ||||||
Rat | RGD:621476 | 65206 | ||||||
Dog | potassium calcium-activated channel subfamily N member 4 | VGNC:42287 | 484464 | |||||
Cow | potassium calcium-activated channel subfamily N member 4 | VGNC:30486 | 534591 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | potassium calcium-activated channel subfamily N member 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | potassium calcium-activated channel subfamily N member 4 | |||||
Cow | potassium calcium-activated channel subfamily N member 4 | |||||
PMID | Text |
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