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Tbio
KANSL1
KAT8 regulatory NSL complex subunit 1

Protein Summary
Description
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262419
  • ENSP00000262419
  • ENSG00000120071
  • ENST00000432791
  • ENSP00000387393
  • ENST00000572904
  • ENSP00000461484
  • ENST00000574590
  • ENSP00000461812

Symbol
  • CENP-36
  • KIAA1267
  • MSL1V1
  • NSL1
  • KDVS
  • NSL1
  • MSL1v1
  • CENP-36
  • hMSL1v1
  • KIAA1267
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
0.87
cellular component
0.78
interacting protein
0.77
virus perturbation
0.68
microRNA
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.37   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.37   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0