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Tbio
JUNB
Transcription factor jun-B

Protein Summary
Description
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302754
  • ENSP00000303315
  • ENSG00000171223

Symbol
  • AP-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
gene perturbation
0.99
transcription factor binding site profile
0.98
PubMedID
0.96
biological process
0.95


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 97.14   (req: < 5)
Gene RIFs: 67   (req: <= 3)
Antibodies: 835   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 97.14   (req: >= 5)
Gene RIFs: 67   (req: > 3)
Antibodies: 835   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 30
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0