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Tbio
ITLN2
Intelectin-2

Protein Summary
Description
May play a role in the defense system against pathogens.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368029
  • ENSP00000357008
  • ENSG00000158764

Symbol
  • HL2
  • HL-2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.41
tissue
0.41
cell line
0.36
biological term
0.33
disease
0.33


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.79   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.79   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (13)
ITLN1
Tbio
Novelty:  0.00299735
p_int:  1
Score:  0.864
Data Source:  BioPlex,STRINGDB
ENDOG
Tbio
Family:  Enzyme
Novelty:  0.00404275
p_int:  0.975229638
p_ni:  0.024770356
p_wrong:  6e-9
Score:  0.874
Data Source:  BioPlex,STRINGDB
SULT2B1
Tbio
Family:  Enzyme
Novelty:  0.02652128
Score:  0.542
Data Source:  STRINGDB
PRG3
Tbio
Novelty:  0.09431986
Score:  0.536
Data Source:  STRINGDB
LGALS14
Tbio
Novelty:  0.08277205
Score:  0.53
Data Source:  STRINGDB
FAM181B
Tdark
Novelty:  0.56210614
Score:  0.473
Data Source:  STRINGDB
IRGC
Tbio
Family:  Enzyme
Novelty:  0.10743948
Score:  0.47
Data Source:  STRINGDB
TFF3
Tbio
Novelty:  0.00127103
Score:  0.449
Data Source:  STRINGDB
RETNLB
Tbio
Novelty:  0.00777842
Score:  0.441
Data Source:  STRINGDB
FCGBP
Tbio
Novelty:  0.02772194
Score:  0.427
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
2
2
2
85.2
monocyte count
3
2
3
79.3
leukocyte count
1
1
1
66.2
1
1
0
1.1
60.6
monocyte percentage of leukocytes
1
1
1
45
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
2
85.2
monocyte count
3
79.3
leukocyte count
1
66.2
0
1.1
60.6
monocyte percentage of leukocytes
1
45
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
intelectin 2
VGNC:1280
457441
Mouse
MGI:1333831
16429
Rat
RGD:1561048
498284
Horse
intelectin-2
100050404
Cow
intelectin 2
618581
Species
Name
OMA
EggNOG
Inparanoid
Chimp
intelectin 2
Mouse
Rat
Horse
intelectin-2
Cow
intelectin 2
Publication Statistics
PubMed Score 10.79
PubMed score by year
PubTator Score 44.14
PubTator score by year
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Related Publications
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PMID
Year
Title