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Tbio
IQCD
Dynein regulatory complex protein 10

Protein Summary
Description
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299732
  • ENSP00000299732
  • ENSG00000166578
  • ENST00000416617
  • ENSP00000400669

Symbol
  • DRC10
  • DRC10
  • CFAP84
  • 4933433C09Rik
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.68
transcription factor
0.59
tissue
0.57
cell type or tissue
0.51
tissue sample
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.45   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.45   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
TNNC1
Tclin
Novelty:  0.03535727
p_int:  0.999229072
p_ni:  3.8e-8
p_wrong:  0.000770891
Data Source:  BioPlex
IQCG
Tbio
Novelty:  0.19968917
Score:  0.821
Data Source:  STRINGDB
IQCA1
Tdark
Novelty:  0.33986781
Score:  0.771
Data Source:  STRINGDB
EFCAB2
Tdark
Novelty:  0.26420728
Score:  0.762
Data Source:  STRINGDB
DRC7
Tdark
Novelty:  0.40606004
Score:  0.753
Data Source:  STRINGDB
TCTE1
Tbio
Novelty:  0.11008102
Score:  0.67
Data Source:  STRINGDB
PRPSAP1
Tbio
Family:  Enzyme
Novelty:  0.08377292
Score:  0.595
Data Source:  STRINGDB
BPIFC
Tdark
Novelty:  0.2764846
Score:  0.59
Data Source:  STRINGDB
FBXL13
Tdark
Novelty:  0.33362589
Score:  0.588
Data Source:  STRINGDB
GYG2
Tbio
Family:  Enzyme
Novelty:  0.01520991
Score:  0.535
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
1
1
1
26.1
response to fenofibrate
1
1
1
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
1
26.1
response to fenofibrate
1
14.2
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
IQ motif containing D
VGNC:5432
452271
Macaque
IQ motif containing D
712904
Mouse
MGI:1922982
75732
Rat
RGD:1560757
498184
Dog
IQ motif containing D
VGNC:52936
611081
Species
Name
OMA
EggNOG
Inparanoid
Chimp
IQ motif containing D
Macaque
IQ motif containing D
Mouse
Rat
Dog
IQ motif containing D
Publication Statistics
PubMed Score 5.45
PubMed score by year
PubTator Score 1.33
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title