IP6K1
Inositol hexakisphosphate kinase 1
Protein Summary
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]
- ENST00000321599
- ENSP00000323780
- ENSG00000176095
- ENST00000395238
- ENSP00000378659
- ENST00000460540
- ENSP00000420762
- ENST00000613416
- ENSP00000482032
- IHPK1
- KIAA0263
- PiUS
- IHPK1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.96 | ||
histone modification site profile | 0.85 | ||
kinase perturbation | 0.84 | ||
transcription factor perturbation | 0.84 | ||
microRNA | 0.71 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 48.27 (req: < 5)
Gene RIFs: 14 (req: <= 3)
Antibodies: 222 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 48.27 (req: >= 5)
Gene RIFs: 14 (req: > 3)
Antibodies: 222 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0