INPP5F
Phosphatidylinositide phosphatase SAC2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.93 | ||
histone modification site profile | 0.91 | ||
transcription factor binding site profile | 0.82 | ||
pathway | 0.72 | ||
gene perturbation | 0.7 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | PI Metabolism | ||||
Reactome | Phospholipid metabolism | ||||
Reactome | Synthesis of PIPs at the early endosome membrane | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of lipids | ||||
PI Metabolism | ||||
Phospholipid metabolism | ||||
Synthesis of PIPs at the early endosome membrane | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
3 | 2 | 1 | 1.4 | 91.7 | |||||
electrocardiography | 1 | 1 | 10 | 84.6 | |||||
4 | 3 | 1 | 1.6 | 84.4 | |||||
2 | 1 | 0 | 1.4 | 82 | |||||
left ventricular ejection fraction measurement | 3 | 2 | 3 | 81.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
1 | 1.4 | 91.7 | |||||
electrocardiography | 10 | 84.6 | |||||
1 | 1.6 | 84.4 | |||||
0 | 1.4 | 82 | |||||
left ventricular ejection fraction measurement | 3 | 81.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | inositol polyphosphate-5-phosphatase F | VGNC:7234 | 450780 | |||||
Macaque | inositol polyphosphate-5-phosphatase F | 703808 | ||||||
Mouse | MGI:2141867 | 101490 | ||||||
Rat | RGD:1305777 | 309008 | ||||||
Dog | inositol polyphosphate-5-phosphatase F | VGNC:42034 | 100856192 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | inositol polyphosphate-5-phosphatase F | |||||
Macaque | inositol polyphosphate-5-phosphatase F | |||||
Mouse | ||||||
Rat | ||||||
Dog | inositol polyphosphate-5-phosphatase F | |||||
PMID | Year | Title |
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