Protein Summary
Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
- ENST00000562441
- ENSP00000456073
- ENSG00000169592
- ENST00000563197
- ENSP00000457016
- ENST00000567065
- ENSP00000454665
- ENST00000620599
- ENSP00000484187
- CCDC95
- CCDC95
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.88 | ||
histone modification site profile | 0.83 | ||
cell type or tissue | 0.7 | ||
cellular component | 0.68 | ||
transcription factor perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.78 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 14 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.78 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 14 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (90)
INO80
Family: Enzyme
Novelty: 0.09412936
p_int: 0.999999968
p_ni: 2.9e-8
p_wrong: 3e-9
Score: 0.999
Data Source: BioPlex,STRINGDB
UCHL5
Family: Enzyme
Novelty: 0.01486265
p_int: 0.999999743
p_ni: 2.56e-7
p_wrong: 1e-9
Score: 0.967
Data Source: BioPlex,STRINGDB
INO80C
Novelty: 0.04242834
p_int: 0.999999245
p_ni: 7.55e-7
Score: 0.951
Data Source: BioPlex,STRINGDB
CCNDBP1
Novelty: 0.01527762
p_int: 0.999985679
p_ni: 0.000013647
p_wrong: 6.73e-7
Score: 0.738
Data Source: BioPlex,STRINGDB
RUVBL2
Novelty: 0.01129017
p_int: 0.99997186
p_ni: 0.000002119
p_wrong: 0.000026021
Score: 0.968
Data Source: BioPlex,STRINGDB
RUVBL1
Novelty: 0.0089115
p_int: 0.999769743
p_ni: 9.48e-7
p_wrong: 0.000229309
Score: 0.972
Data Source: BioPlex,STRINGDB
BCL7A
Novelty: 0.07026394
p_int: 0.997135862
p_ni: 0.000337103
p_wrong: 0.002527035
Score: 0.19
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (8)
Reactome (8)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Damage Recognition in GG-NER | ||||
Reactome | DNA Repair | ||||
Reactome | Deubiquitination | ||||
Reactome | Global Genome Nucleotide Excision Repair (GG-NER) | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Damage Recognition in GG-NER | ||||
DNA Repair | ||||
Deubiquitination | ||||
Global Genome Nucleotide Excision Repair (GG-NER) | ||||
Metabolism of proteins | ||||
Viral Interactions (0)
Gene Ontology Terms (8)
Components (4)
Processes (4)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from Direct Assay (IDA) | HPA | |||
Traceable Author Statement (TAS) | Reactome | |||
Disease Associations (null)
GWAS Traits (49)
Items per page:
1 – 5 of 49
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 6 | 5 | 6 | 96.4 | |||||
appendicular lean mass | 2 | 3 | 6 | 94.7 | |||||
mean corpuscular volume | 3 | 2 | 3 | 94 | |||||
waist-hip ratio | 3 | 3 | 3 | 89.1 | |||||
red blood cell density measurement | 2 | 1 | 2 | 87.3 | |||||
Items per page:
1 – 5 of 49
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 6 | 96.4 | |||||
appendicular lean mass | 6 | 94.7 | |||||
mean corpuscular volume | 3 | 94 | |||||
waist-hip ratio | 3 | 89.1 | |||||
red blood cell density measurement | 2 | 87.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | INO80 complex subunit E | 708115 | ||||||
Mouse | MGI:2141881 | 233875 | ||||||
Rat | RGD:1359572 | 293494 | ||||||
Dog | INO80 complex subunit E | VGNC:42026 | 489944 | |||||
Horse | INO80 complex subunit E | VGNC:19068 | 100064084 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | INO80 complex subunit E | |||||
Mouse | ||||||
Rat | ||||||
Dog | INO80 complex subunit E | |||||
Horse | INO80 complex subunit E | |||||
Publication Statistics
PubMed Score 1.78
PubMed score by year
PubTator Score 1.09
PubTator score by year
Related Publications
Text Mined References (13)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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