INO80
Chromatin-remodeling ATPase INO80
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.98 | ||
transcription factor binding site profile | 0.95 | ||
histone modification site profile | 0.92 | ||
hub protein | 0.9 | ||
virus perturbation | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Damage Recognition in GG-NER | ||||
Reactome | DNA Repair | ||||
Reactome | Deubiquitination | ||||
Reactome | Global Genome Nucleotide Excision Repair (GG-NER) | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Damage Recognition in GG-NER | ||||
DNA Repair | ||||
Deubiquitination | ||||
Global Genome Nucleotide Excision Repair (GG-NER) | ||||
Metabolism of proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 6 | 6 | 6 | 7.4 | 96 | ||||
hemoglobin measurement | 2 | 2 | 2 | 64.8 | |||||
intelligence | 3 | 2 | 1 | 5.6 | 57.6 | ||||
hematocrit | 1 | 1 | 1 | 51.7 | |||||
BMI-adjusted waist circumference | 1 | 2 | 2 | 50.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 6 | 7.4 | 96 | ||||
hemoglobin measurement | 2 | 64.8 | |||||
intelligence | 1 | 5.6 | 57.6 | ||||
hematocrit | 1 | 51.7 | |||||
BMI-adjusted waist circumference | 2 | 50.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | INO80 complex subunit | VGNC:1927 | 453346 | |||||
Mouse | MGI:1915392 | 68142 | ||||||
Rat | RGD:1310969 | 296084 | ||||||
Dog | INO80 complex subunit | VGNC:42024 | 478262 | |||||
Horse | INO80 complex subunit | VGNC:19067 | 100057033 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | INO80 complex subunit | |||||
Mouse | ||||||
Rat | ||||||
Dog | INO80 complex subunit | |||||
Horse | INO80 complex subunit | |||||
PMID | Year | Title |
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