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Tdark
ILDR2
Immunoglobulin-like domain-containing receptor 2

Protein Summary
Description
May be involved in lipid homeostasis and ER stress pathways.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000271417
  • ENSP00000271417
  • ENSG00000143195

Symbol
  • C1orf32
  • C1orf32
  • dJ782G3.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.86
histone modification site profile
0.75
cell type or tissue
0.68
tissue sample
0.52
cell line
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.2   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 40   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.2   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
HFE
Tbio
Novelty:  0.00042077
p_int:  0.808796132
p_ni:  0.000024633
p_wrong:  0.191179235
Data Source:  BioPlex
C1QTNF4
Tbio
Novelty:  0.10701626
Score:  0.739
Data Source:  STRINGDB
MARVELD2
Tbio
Novelty:  0.01228406
Score:  0.672
Data Source:  STRINGDB
ZFP69
Tdark
Family:  TF
Novelty:  0.45110932
Score:  0.588
Data Source:  STRINGDB
TUBD1
Tbio
Novelty:  0.03591414
Score:  0.575
Data Source:  STRINGDB
SORCS1
Tbio
Novelty:  0.03148473
Score:  0.571
Data Source:  STRINGDB
TBC1D1
Tbio
Novelty:  0.0122464
Score:  0.538
Data Source:  STRINGDB
TRA2A
Tbio
Novelty:  0.04935993
Score:  0.518
Data Source:  STRINGDB
TRA2B
Tbio
Novelty:  0.0146833
Score:  0.511
Data Source:  STRINGDB
SRSF5
Tbio
Novelty:  0.01658346
Score:  0.51
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
3
2
3
74.5
myeloid white cell count
1
1
1
57.7
leukocyte count
3
3
3
53.2
brain measurement
1
1
0
7
43.2
neutrophil percentage of leukocytes
1
1
1
25.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
3
74.5
myeloid white cell count
1
57.7
leukocyte count
3
53.2
brain measurement
0
7
43.2
neutrophil percentage of leukocytes
1
25.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin like domain containing receptor 2
VGNC:6888
457483
Macaque
immunoglobulin like domain containing receptor 2
699899
Mouse
MGI:1196370
100039795
Rat
RGD:1596420
685277
Dog
immunoglobulin like domain containing receptor 2
VGNC:41998
490364
Species
Name
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin like domain containing receptor 2
Macaque
immunoglobulin like domain containing receptor 2
Mouse
Rat
Dog
immunoglobulin like domain containing receptor 2
Publication Statistics
PubMed Score 7.20
PubMed score by year
PubTator Score 3.48
PubTator score by year
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Related Publications
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PMID
Year
Title