IL7R
Interleukin-7 receptor subunit alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 1 | ||
hub protein | 0.98 | ||
transcription factor perturbation | 0.97 | ||
biological process | 0.86 | ||
disease | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cargo recognition for clathrin-mediated endocytosis | ||||
Reactome | Clathrin-mediated endocytosis | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | Interleukin-7 signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cargo recognition for clathrin-mediated endocytosis | ||||
Clathrin-mediated endocytosis | ||||
Cytokine Signaling in Immune system | ||||
Immune System | ||||
Interleukin-7 signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 3 | 3 | 96.5 | |||||
6 | 4 | 0 | 1.1 | 95.7 | |||||
lymphocyte percentage of leukocytes | 2 | 2 | 2 | 93.8 | |||||
4 | 3 | 0 | 1.1 | 93.8 | |||||
neutrophil percentage of leukocytes | 2 | 2 | 2 | 92.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 96.5 | |||||
0 | 1.1 | 95.7 | |||||
lymphocyte percentage of leukocytes | 2 | 93.8 | |||||
0 | 1.1 | 93.8 | |||||
neutrophil percentage of leukocytes | 2 | 92.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | interleukin 7 receptor | VGNC:13516 | 461922 | |||||
Macaque | interleukin 7 receptor | 699869 | ||||||
Mouse | MGI:96562 | 16197 | ||||||
Rat | RGD:1309776 | 294797 | ||||||
Dog | interleukin 7 receptor | VGNC:41996 | 612582 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | interleukin 7 receptor | |||||
Macaque | interleukin 7 receptor | |||||
Mouse | ||||||
Rat | ||||||
Dog | interleukin 7 receptor | |||||
PMID | Year | Title |
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