IL1R2
Interleukin-1 receptor type 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.96 | ||
protein domain | 0.92 | ||
disease | 0.79 | ||
small molecule perturbation | 0.71 | ||
transcription factor perturbation | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | Interleukin-1 family signaling | ||||
Reactome | Interleukin-1 signaling | ||||
Reactome | Interleukin-10 signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Immune System | ||||
Interleukin-1 family signaling | ||||
Interleukin-1 signaling | ||||
Interleukin-10 signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
2 | 2 | 0 | 1.1 | 62.8 | |||||
C-reactive protein measurement | 2 | 2 | 2 | 54.3 | |||||
fibrinogen measurement | 4 | 2 | 4 | 54.2 | |||||
ST2 protein measurement | 1 | 1 | 1 | 39.4 | |||||
albumin:globulin ratio measurement | 1 | 1 | 1 | 33.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 62.8 | |||||
C-reactive protein measurement | 2 | 54.3 | |||||
fibrinogen measurement | 4 | 54.2 | |||||
ST2 protein measurement | 1 | 39.4 | |||||
albumin:globulin ratio measurement | 1 | 33.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | interleukin 1 receptor type 2 | VGNC:10291 | 470455 | |||||
Macaque | interleukin 1 receptor type 2 | 711638 | ||||||
Mouse | MGI:96546 | 16178 | ||||||
Rat | RGD:621147 | 117022 | ||||||
Dog | interleukin 1 receptor type 2 | VGNC:41959 | 481330 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | interleukin 1 receptor type 2 | |||||
Macaque | interleukin 1 receptor type 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | interleukin 1 receptor type 2 | |||||
PMID | Year | Title |
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