IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 1 | ||
biological term | 0.99 | ||
chemical | 0.99 | ||
kinase | 0.99 | ||
molecular function | 0.99 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of NF-kappaB in B cells | ||||
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing-Cross presentation | ||||
Reactome | C-type lectin receptors (CLRs) | ||||
Reactome | CLEC7A (Dectin-1) signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of NF-kappaB in B cells | ||||
Adaptive Immune System | ||||
Antigen processing-Cross presentation | ||||
C-type lectin receptors (CLRs) | ||||
CLEC7A (Dectin-1) signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
tissue plasminogen activator measurement | 1 | 2 | 2 | 49.2 | |||||
1 | 1 | 0 | 1.9 | 17.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
tissue plasminogen activator measurement | 2 | 49.2 | |||||
0 | 1.9 | 17.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | inhibitor of nuclear factor kappa B kinase subunit beta | 704683 | ||||||
Mouse | MGI:1338071 | 16150 | ||||||
Rat | RGD:621375 | 84351 | ||||||
Dog | inhibitor of nuclear factor kappa B kinase subunit beta | VGNC:51803 | 482839 | |||||
Cow | inhibitor of nuclear factor kappa B kinase subunit beta | 281854 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | inhibitor of nuclear factor kappa B kinase subunit beta | |||||
Mouse | ||||||
Rat | ||||||
Dog | inhibitor of nuclear factor kappa B kinase subunit beta | |||||
Cow | inhibitor of nuclear factor kappa B kinase subunit beta | |||||
PMID | Year | Title |
---|