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Tbio
IGSF6
Immunoglobulin superfamily member 6

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000268389
  • ENSP00000268389
  • ENSG00000140749
  • ENST00000639480
  • ENSP00000491064
  • ENSG00000283934

Symbol
  • DORA
  • DORA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
tissue sample
0.62
gene perturbation
0.59
protein domain
0.58
co-expressed gene
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.57   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 172   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.57   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (80)
GNPTAB
Tbio
Family:  Enzyme
Novelty:  0.00336101
p_int:  0.999632964
p_ni:  0.000367035
p_wrong:  1e-9
Score:  0.187
Data Source:  BioPlex,STRINGDB
RANGRF
Tbio
Family:  Enzyme
Novelty:  0.02750539
p_int:  0.981363371
p_ni:  0.001728712
p_wrong:  0.016907916
Score:  0.188
Data Source:  BioPlex,STRINGDB
AP3S1
Tbio
Novelty:  0.12425009
p_int:  0.929855255
p_ni:  0.070144745
p_wrong:  1e-9
Score:  0.179
Data Source:  BioPlex,STRINGDB
CWC27
Tbio
Family:  Enzyme
Novelty:  0.15135654
p_int:  0.925275091
p_ni:  0.074724909
Score:  0.309
Data Source:  BioPlex,STRINGDB
CETN3
Tbio
Novelty:  0.00705513
p_int:  0.909804014
p_ni:  0.090195971
p_wrong:  1.5e-8
Score:  0.187
Data Source:  BioPlex,STRINGDB
CANX
Tbio
Novelty:  0.00087002
p_int:  0.786776681
p_ni:  0.213223319
Data Source:  BioPlex
METTL9
Tdark
Family:  Enzyme
Novelty:  0.20589257
Score:  0.931
Data Source:  STRINGDB
TYROBP
Tbio
Family:  Enzyme
Novelty:  0.00410031
Score:  0.813
Data Source:  STRINGDB
CSF1R
Tclin
Family:  Kinase
Novelty:  0.00064143
Score:  0.771
Data Source:  STRINGDB
ITGAX
Tbio
Novelty:  0.00040471
Score:  0.746
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
3
1
1
96.5
3
3
1
1
96.5
balding measurement
1
1
1
79.2
balding measurement
1
1
1
79.2
inflammatory biomarker measurement
1
1
0
53.4
48.5
Items per page:
1 – 5 of 8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
96.5
1
1
96.5
balding measurement
1
79.2
balding measurement
1
79.2
inflammatory biomarker measurement
0
53.4
48.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin superfamily member 6
VGNC:5805
743102
Macaque
immunoglobulin superfamily member 6
699485
Mouse
MGI:1891393
80719
Rat
RGD:620663
171064
Dog
immunoglobulin superfamily member 6
VGNC:41917
100684869
Species
Name
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin superfamily member 6
Macaque
immunoglobulin superfamily member 6
Mouse
Rat
Dog
immunoglobulin superfamily member 6
Publication Statistics
PubMed Score 13.57
PubMed score by year
PubTator Score 19.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title