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Tbio
IFT22
Intraflagellar transport protein 22 homolog

Protein Summary
Description
Small GTPase-like component of the intraflagellar transport (IFT) complex B.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315322
  • ENSP00000320359
  • ENSG00000128581
  • ENST00000422177
  • ENSP00000392087
  • ENST00000437644
  • ENSP00000390770
  • ENST00000498704
  • ENSP00000429648
  • ENST00000517481
  • ENSP00000429202
  • ENST00000621899
  • ENSP00000478948

Symbol
  • RABL5
  • RABL5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
molecular function
0.9
cell type or tissue
0.81
transcription factor perturbation
0.68
cellular component
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (114)
IFT52
Tbio
Novelty:  0.04183122
p_int:  0.999999991
p_ni:  9e-9
Score:  0.983
Data Source:  BioPlex,STRINGDB
IFT88
Tbio
Novelty:  0.00727114
p_int:  0.999999958
p_ni:  4.2e-8
Score:  0.979
Data Source:  BioPlex,STRINGDB
IFT80
Tbio
Novelty:  0.04862973
p_int:  0.999999957
p_ni:  4.3e-8
Score:  0.981
Data Source:  BioPlex,STRINGDB
CLUAP1
Tbio
Novelty:  0.08002286
p_int:  0.999999953
p_ni:  4.7e-8
Score:  0.976
Data Source:  BioPlex,STRINGDB
TRAF3IP1
Tbio
Novelty:  0.0668178
p_int:  0.999999878
p_ni:  1.22e-7
Score:  0.984
Data Source:  BioPlex,STRINGDB
IFT46
Tdark
Novelty:  0.11310911
p_int:  0.999999759
p_ni:  2.41e-7
Score:  0.987
Data Source:  BioPlex,STRINGDB
IFT81
Tbio
Novelty:  0.01610195
p_int:  0.999999726
p_ni:  2.74e-7
Score:  0.985
Data Source:  BioPlex,STRINGDB
TTC30A
Tdark
Novelty:  1.41742212
p_int:  0.999999652
p_ni:  3.47e-7
p_wrong:  2e-9
Score:  0.993
Data Source:  BioPlex,STRINGDB
TTC30B
Tbio
Novelty:  0.10944566
p_int:  0.99999719
p_ni:  0.00000281
Score:  0.994
Data Source:  BioPlex,STRINGDB
UACA
Tbio
Novelty:  0.05853699
p_int:  0.999992111
p_ni:  0.000007889
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Cilium Assembly (R-HSA-5617833)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cilium Assembly
Reactome
Intraflagellar transport
Reactome
Organelle biogenesis and maintenance
Name
Explore in Pharos
Explore in Source
Cilium Assembly
Intraflagellar transport
Organelle biogenesis and maintenance
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
1
1
53.3
intraocular pressure measurement
1
2
2
39.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
53.3
intraocular pressure measurement
2
39.4
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
intraflagellar transport 22
VGNC:4395
741533
Mouse
MGI:1914536
67286
Rat
RGD:1305370
288585
Dog
intraflagellar transport 22
VGNC:54035
479727
Horse
intraflagellar transport 22
VGNC:51158
100060333
Species
Name
OMA
EggNOG
Inparanoid
Chimp
intraflagellar transport 22
Mouse
Rat
Dog
intraflagellar transport 22
Horse
intraflagellar transport 22
Publication Statistics
PubMed Score 6.94
PubMed score by year
PubTator Score 0.42
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title