Tbio IFNA1 Interferon alpha-1/13

Protein Summary

Description

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]

Uniprot Accession IDs

• P01562
• D4Q9M8
• Q14605
• Q2M1L8
• Q52LB8
• Q5VYQ2
• Q7M4Q1
• Q8WZ68
• Q9UMJ3
• IFN-alpha-1/13

Gene Name

• IFNA1

Ensembl ID

• ENST00000276927
• ENSP00000276927
• ENSG00000197919
• ENST00000449498
• ENSP00000394494
• ENSG00000233816

Symbol

• IFL
• IFN
• IFNA@
• IFNA13
• IFN-ALPHA
• IFN-alphaD

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.64
cell line	0.46
phenotype	0.42
gene perturbation	0.36
transcription factor	0.36

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11739.9   (req: < 5)

Gene RIFs: 268   (req: <= 3)

Antibodies: 823   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11739.9   (req: >= 5)

Gene RIFs: 268   (req: > 3)

Antibodies: 823   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0