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Tdark
IFITM10
Interferon-induced transmembrane protein 10

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340134
  • ENSP00000344430
  • ENSG00000244242

Symbol
  • DSPA3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.81
tissue
0.47
microRNA
0.46
cell line
0.44
tissue sample
0.38


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (17)
IRF6
Tbio
Family:  TF
Novelty:  0.00209286
Score:  0.593
Data Source:  STRINGDB
PGGHG
Tbio
Family:  Enzyme
Novelty:  0.40196205
Score:  0.568
Data Source:  STRINGDB
TMEM233
Tdark
Novelty:  3.56925193
Score:  0.55
Data Source:  STRINGDB
MOB2
Tbio
Family:  Enzyme
Novelty:  0.02691673
Score:  0.545
Data Source:  STRINGDB
KRTAP5-1
Tdark
Novelty:  0.83665339
Score:  0.54
Data Source:  STRINGDB
UCHL1
Tchem
Family:  Enzyme
Novelty:  0.00056075
Score:  0.514
Data Source:  STRINGDB
B4GALNT4
Tdark
Family:  Enzyme
Novelty:  0.19278471
Score:  0.508
Data Source:  STRINGDB
TRIML1
Tdark
Family:  Enzyme
Novelty:  0.63862986
Score:  0.502
Data Source:  STRINGDB
SCNN1A
Tclin
Family:  IC
Novelty:  0.00900102
Score:  0.473
Data Source:  STRINGDB
CHMP5
Tbio
Novelty:  0.03378716
Score:  0.461
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cathepsin D measurement
1
3
3
96.9
blood protein measurement
1
1
1
82.8
aspartate aminotransferase measurement
1
1
0
7.1
56
hematocrit
1
1
1
15.5
hemoglobin measurement
1
1
1
9.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cathepsin D measurement
3
96.9
blood protein measurement
1
82.8
aspartate aminotransferase measurement
0
7.1
56
hematocrit
1
15.5
hemoglobin measurement
1
9.9
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2444776
320802
Rat
Dog
interferon induced transmembrane protein 10
VGNC:51876
611537
Cow
interferon induced transmembrane protein 10
VGNC:30052
613464
Anole lizard
interferon induced transmembrane protein 10
100567436
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
interferon induced transmembrane protein 10
Cow
interferon induced transmembrane protein 10
Anole lizard
interferon induced transmembrane protein 10
Publication Statistics
PubMed Score 3.11
PubMed score by year
PubTator Score 2.45
PubTator score by year
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Related Publications
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PMID
Year
Title