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Tbio
IFI35
Interferon-induced 35 kDa protein

Protein Summary
Description
Not yet known.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000415816
  • ENSP00000394579
  • ENSG00000068079
  • ENST00000438323
  • ENSP00000395590

Symbol
  • IFP35
  • IFP35
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
gene perturbation
0.91
PubMedID
0.79
kinase perturbation
0.71
transcription factor perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.38   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 289   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.38   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 289   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (169)
NMI
Tbio
Novelty:  0.06987427
p_int:  0.999999134
p_wrong:  8.66e-7
Score:  0.985
Data Source:  BioPlex,STRINGDB
PLXNA1
Tbio
Novelty:  0.01195083
p_int:  0.980820112
p_ni:  0.019179888
Data Source:  BioPlex
NFRKB
Tbio
Novelty:  0.13445983
p_int:  0.92760348
p_ni:  0.07239652
Data Source:  BioPlex
CYTH3
Tbio
Novelty:  0.00940752
p_int:  0.895699573
p_ni:  0.104300426
p_wrong:  1e-9
Score:  0.211
Data Source:  BioPlex,STRINGDB
IRF7
Tbio
Family:  TF
Novelty:  0.0021839
Score:  0.992
Data Source:  STRINGDB
IFIT3
Tbio
Novelty:  0.00568113
Score:  0.992
Data Source:  STRINGDB
ISG15
Tbio
Novelty:  0.00203781
Score:  0.99
Data Source:  STRINGDB
OAS1
Tbio
Family:  Enzyme
Novelty:  0.00532331
Score:  0.99
Data Source:  STRINGDB
MX1
Tbio
Novelty:  0.00072554
Score:  0.989
Data Source:  STRINGDB
OAS3
Tbio
Family:  Enzyme
Novelty:  0.02422229
Score:  0.989
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (17)
Cytokine Signaling in Immune system (R-HSA-1280215)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cytokine Signaling in Immune system
Reactome
Immune System
Reactome
Interferon Signaling
Reactome
Interferon alpha/beta signaling
Name
Explore in Pharos
Explore in Source
Cytokine Signaling in Immune system
Immune System
Interferon Signaling
Interferon alpha/beta signaling
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Traceable Author Statement (TAS)
Reactome
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
2
2
87.8
myeloid white cell count
1
1
1
71.9
aspartate aminotransferase measurement
1
1
0
7.1
55.2
leukocyte count
1
1
1
55.2
age at menopause
1
1
1
45.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
87.8
myeloid white cell count
1
71.9
aspartate aminotransferase measurement
0
7.1
55.2
leukocyte count
1
55.2
age at menopause
1
45.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
interferon induced protein 35
VGNC:9330
741105
Macaque
interferon induced protein 35
712409
Mouse
MGI:1917360
70110
Rat
RGD:1304553
287719
Dog
interferon induced protein 35
VGNC:41872
490954
Species
Name
OMA
EggNOG
Inparanoid
Chimp
interferon induced protein 35
Macaque
interferon induced protein 35
Mouse
Rat
Dog
interferon induced protein 35
Publication Statistics
PubMed Score 29.38
PubMed score by year
PubTator Score 14.54
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title