Tbio IFFO1 Intermediate filament family orphan 1

Protein Summary

Description

This gene is a member of the intermediate filament family. Intermediate filaments are proteins which are primordial components of the cytoskeleton and nuclear envelope. The proteins encoded by the members of this gene family are evolutionarily and structurally related but have limited sequence homology, with the exception of the central rod domain. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Uniprot Accession IDs

• Q0D2I5
• Q24JT6
• Q7L5J9
• Q7Z5X4
• Q9BQ46

Gene Name

• IFFO1

Ensembl ID

• ENST00000336604
• ENSP00000337593
• ENSG00000010295
• ENST00000356896
• ENSP00000349364
• ENST00000396840
• ENSP00000380052
• ENST00000487279
• ENSP00000432493

Symbol

• IFFO
• IFFO
• HOM-TES-103

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.92
disease perturbation	0.79
kinase perturbation	0.71
cell type or tissue	0.7
tissue sample	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.53   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 60   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.53   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0