HSPA8
Heat shock cognate 71 kDa protein
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 1 | ||
interacting protein | 1 | ||
kinase perturbation | 1 | ||
molecular function | 1 | ||
virus perturbation | 1 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | AUF1 (hnRNP D0) binds and destabilizes mRNA | ||||
Reactome | Attenuation phase | ||||
Reactome | Autophagy | ||||
Reactome | Axon guidance | ||||
Reactome | CHL1 interactions | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
AUF1 (hnRNP D0) binds and destabilizes mRNA | ||||
Attenuation phase | ||||
Autophagy | ||||
Axon guidance | ||||
CHL1 interactions | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | ARUK-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | ParkinsonsUK-UCL | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | ARUK-UCL | |||
Inferred from Physical Interaction (IPI) | ParkinsonsUK-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 3 | 4 | 92.2 | |||||
mean corpuscular hemoglobin concentration | 4 | 3 | 4 | 90 | |||||
age at menarche | 2 | 2 | 1 | 2.7 | 78.4 | ||||
myeloid white cell count | 1 | 1 | 1 | 39.6 | |||||
BMI-adjusted hip circumference | 1 | 2 | 2 | 39.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 92.2 | |||||
mean corpuscular hemoglobin concentration | 4 | 90 | |||||
age at menarche | 1 | 2.7 | 78.4 | ||||
myeloid white cell count | 1 | 39.6 | |||||
BMI-adjusted hip circumference | 2 | 39.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | heat shock protein family A (Hsp70) member 8 | VGNC:11823 | 451629 | |||||
Macaque | heat shock protein family A (Hsp70) member 8 | 707989 | ||||||
Mouse | MGI:105384 | 15481 | ||||||
Rat | RGD:621725 | 24468 | ||||||
Dog | heat shock protein family A (Hsp70) member 8 | 479406 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | heat shock protein family A (Hsp70) member 8 | |||||
Macaque | heat shock protein family A (Hsp70) member 8 | |||||
Mouse | ||||||
Rat | ||||||
Dog | heat shock protein family A (Hsp70) member 8 | |||||
PMID | Year | Title |
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