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Tdark
HSP90AB4P
Putative heat shock protein HSP 90-beta 4

Protein Summary
Description
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
Uniprot Accession IDs
Gene Name
Symbol
  • HSP90Bd
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.63
interacting protein
0.61
cell type or tissue
0.52
chemical
0.41
tissue sample
0.26


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
AKT3
Tchem
Family:  Kinase
Novelty:  0.00308931
p_int:  0.999999931
p_ni:  6.9e-8
Data Source:  BioPlex
HSP90AB1
Tchem
Novelty:  0.00907961
p_int:  0.999999926
p_ni:  7.4e-8
Data Source:  BioPlex
SMYD3
Tchem
Family:  Epigenetic
Novelty:  0.01040802
p_int:  0.999999635
p_ni:  3.65e-7
Data Source:  BioPlex
CDK9
Tchem
Family:  Kinase
Novelty:  0.00210218
p_int:  0.999999442
p_ni:  5.58e-7
Data Source:  BioPlex
RPS6KA4
Tchem
Family:  Kinase
Novelty:  0.05213255
p_int:  0.99999927
p_ni:  7.3e-7
Data Source:  BioPlex
CDK3
Tchem
Family:  Kinase
Novelty:  0.03380289
p_int:  0.999999075
p_ni:  9.22e-7
p_wrong:  2e-9
Data Source:  BioPlex
PINK1
Tbio
Family:  Kinase
Novelty:  0.00100973
p_int:  0.99999875
p_ni:  0.00000125
Data Source:  BioPlex
MYLK4
Tchem
Family:  Kinase
Novelty:  0.14967851
p_int:  0.999998551
p_ni:  0.000001449
Data Source:  BioPlex
STK35
Tchem
Family:  Kinase
Novelty:  0.19556072
p_int:  0.999994841
p_ni:  0.000005157
p_wrong:  2e-9
Data Source:  BioPlex
CDK7
Tchem
Family:  Kinase
Novelty:  0.00322814
p_int:  0.999993981
p_ni:  0.000006018
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
No publication or patent stats found
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Related Publications
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Year
Title