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Tbio
HSFY1
Heat shock transcription factor, Y-linked

Protein Summary
Description
This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304790
  • ENSP00000306549
  • ENSG00000169953
  • ENST00000307393
  • ENSP00000303599
  • ENSG00000172468
  • ENST00000309834
  • ENSP00000311166
  • ENST00000338876
  • ENSP00000342302
  • ENST00000344884
  • ENSP00000340971
  • ENST00000382852
  • ENSP00000372303
  • ENST00000382856
  • ENSP00000372307

Symbol
  • HSF2L
  • HSFY
  • HSFY
  • HSF2L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.47
tissue
0.45
cellular component
0.39
biological term
0.35
virus perturbation
0.32


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0