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Tbio
HPX
Hemopexin

Protein Summary
Description
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265983
  • ENSP00000265983
  • ENSG00000110169

Symbol
  • HX
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.91
gene perturbation
0.83
cell type or tissue
0.69
cell line
0.64
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 739.97   (req: < 5)
Gene RIFs: 32   (req: <= 3)
Antibodies: 520   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 739.97   (req: >= 5)
Gene RIFs: 32   (req: > 3)
Antibodies: 520   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0