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Tbio
HMG20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

Protein Summary
Description
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333651
  • ENSP00000328269
  • ENSG00000064961

Symbol
  • BRAF35
  • HMGX2
  • HMGXB2
  • SMARCE1R
  • SOXL
  • HMGX2
  • BRAF25
  • BRAF35
  • HMGXB2
  • PP7706
  • pp8857
  • SMARCE1r
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.84
histone modification site profile
0.83
protein complex
0.74
biological process
0.72
transcription factor
0.69


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.62   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 274   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.62   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 274   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0