Protein Summary
This gene encodes a protein that belongs to the glucose/sorbosone dehydrogenase family. The encoded protein also contains a domain that binds folate and reduced folic acid derivatives. [provided by RefSeq, Jul 2016]
- ENST00000330710
- ENSP00000330601
- ENSG00000182218
- ENST00000357223
- ENSP00000349757
- HHIP2
- KIAA1822
- UNQ9245
- KIAA1822
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.85 | ||
PubMedID | 0.65 | ||
histone modification site profile | 0.62 | ||
tissue sample | 0.55 | ||
microRNA | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.84 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 53 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.84 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 53 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (44)
ITPA
Family: Enzyme
Novelty: 0.00235169
p_int: 0.998908318
p_ni: 0.001091578
p_wrong: 1.04e-7
Data Source: BioPlex
DHRS4
Family: Enzyme
Novelty: 0.02992279
p_int: 0.966121992
p_ni: 0.033438359
p_wrong: 0.000439649
Data Source: BioPlex
MAP7
Novelty: 0.01976296
p_int: 0.957580997
p_ni: 0.042318919
p_wrong: 0.000100085
Data Source: BioPlex
DDX11
Family: Enzyme
Novelty: 0.02282234
p_int: 0.957116134
p_ni: 0.02554453
p_wrong: 0.017339336
Data Source: BioPlex
ACOT9
Family: Enzyme
Novelty: 0.17405187
p_int: 0.932512124
p_ni: 0.06748777
p_wrong: 1.06e-7
Data Source: BioPlex
CDC7
Family: Kinase
Novelty: 0.00435359
p_int: 0.760184018
p_ni: 0.239815982
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (2)
Components (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
8 | 5 | 4 | 1.1 | 91.4 | |||||
1 | 1 | 0 | 1.1 | 31.4 | |||||
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
4 | 1.1 | 91.4 | |||||
0 | 1.1 | 31.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | HHIP like 1 | VGNC:12782 | 100613836 | |||||
Macaque | HHIP like 1 | 717012 | ||||||
Mouse | MGI:1919265 | 214305 | ||||||
Rat | RGD:1311698 | 362781 | ||||||
Dog | HHIP like 1 | VGNC:53497 | 612500 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | HHIP like 1 | |||||
Macaque | HHIP like 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | HHIP like 1 | |||||
Publication Statistics
PubMed Score 1.84
PubMed score by year
PubTator Score 0.97
PubTator score by year
Related Publications
Text Mined References (8)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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